Biopharmax is an engineering company established 40 years ago that focuses on the pharmaceutical industry. It has designed and constructed over 100 facilities in 14 countries around the globe and is actively present in Europe, China, India and the Middle East.
The company's mission is to design build and validate pharmaceutical facilities of the highest level and has a proven track record of handling and addressing the most advanced biotechnology processes and products.
Biopharmax integrates Rockwell Automation products in several of the customer facilities it designs and constructs, including a recent project for Pluristem in the field of Stem Cell growth and final therapy dose production. The Pluristem's requirement is for Biopharmax to set up a state-of-the-art facility – the first of its kind in the world – that can produce final Stem Cell therapy products on a commercial scale.
According to Solomon Gahtan, Business Development Manager at Biopharmax: “We have a unique model where we will design a factory from the start, construct it in its entirety and then validate it to make sure it is prepared for regulatory approval such as USFDA. We hand over at the approval stage and then take responsibility remedying any issues.
Not all companies work this way; some will use a designer and then various sub contractors. In this instance you often get a dispersed control system for each of the individual elements of the factory. In our case, we take the plant as one, including the HVAC, plant utilities, critical systems, such as Purified Water (PuW) Water For Injection (WFI) and Pure Steam (PS), and other production elements.
“In doing so, we can better protect sensitive product batches from any variance in the plant conditions as room temperature, humidity and cleanliness,” he continues. “We can better monitor the various parameters and, when required, enhance the necessary remedial action activated by the control system itself. This may turn out critical for protection of the product batches during the production stage. We can also achieve better optimisation of energy consumption by the HVAC system and reduce unnecessary OPEX. The ControlLogix PLC-based solution helps towards the reliability and flexibility needed to achieve these goals, and we find the Rockwell Automation system of to be a light system and of the appropriate size that allows us to provide these advantages even for a small or medium plant.”